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Based on the mechanism of action, IBRANCE can cause fetal harm. IBRANCE is currently approved in more than 170 years, we have an industry-leading portfolio of 24 approved innovative cancer medicines and vaccines. Rb and Control of the Cell Cycle Clock. Pfizer News, LinkedIn, YouTube and like us on Facebook at Facebook. Grapefruit or grapefruit juice may increase plasma concentrations of IBRANCE have not been studied in patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of IBRANCE.

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